R&D Briefings2025-06-17T13:04:22+00:00

R&D Briefings

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CIRS RD Briefing 102 – Tracking Availability in China of Medicines Approved in Six Key Global Markets

All approved medicines have been rigorously assessed by regulatory authorities to ensure their benefits outweigh the risks. Today, pharmaceutical companies are increasingly focused on integrated global drug development strategies, [...]

September 16th, 2025|

CIRS RD Briefing 99 – First HTA outcomes and timelines for oncology medicines approved by EMA 2018-2023

This R&D Briefing presents data from HTADock, an ongoing CIRS benchmarking study that collects publicly available data on new active substances (NASs) appraised by key international HTA agencies. This CIRS [...]

August 11th, 2025|

CIRS RD Briefing 101 – New drug approvals by six major authorities 2015-2024

This R&D Briefing presents the results from the Centre for Innovation in Regulatory Science (CIRS) annual analysis of new active substance (NAS) approvals by six major regulatory agencies: the [...]

August 6th, 2025|

CIRS RD Briefing 97 – Access Consortium and Project Orbis Approvals Across Eight Regulators

This R&D Briefing builds upon the Centre for Innovation in Regulatory Science (CIRS)'s long-standing efforts to examine trends and practices in regulatory approvals. For over 20 years, CIRS has [...]

March 31st, 2025|

CIRS RD Briefing 98 – European HTA trends: HTA outcomes and timelines across seven markets 2019-2023

This R&D Briefing presents data from HTADock, an ongoing CIRS metrics study that collects publicly available data on new active substances (NASs) appraised by key international HTA agencies. It [...]

March 5th, 2025|

CIRS RD Briefing 96 – Review of HTA outcomes and timelines in Australia, Canada and the UK 2019-2023

This R&D Briefing presents data from HTADock, an ongoing metrics study that collects publicly available data on new active substances (NASs) appraised by key international HTA agencies. It focuses [...]

November 7th, 2024|

CIRS RD Briefing 95 – Review of HTA outcomes and timelines in Australia, Canada, Europe and the UK 2019-2023

This R&D Briefing presents data from HTADock, an ongoing metrics study that collects publicly available data on new active substances (NASs) appraised by key international HTA agencies, each with [...]

August 28th, 2024|

CIRS RD Briefing 93 – New drug approvals by six major authorities 2014-2023

This R&D Briefing presents the results from the Centre for Innovation in Regulatory Science (CIRS) annual analysis of new active substance (NAS) approvals by six major regulatory agencies: the [...]

July 9th, 2024|

CIRS RD Briefing 94 – Value of Reference Agency Reports in Enabling Reliance

Access to information, including the assessment documents of reference national regulatory agencies (NRA), is a key enabler of regulatory risk-based decision making. It promotes an understanding of what was [...]

June 20th, 2024|

CIRS RD Briefing 92 – Appraising the usability of public assessment reports for reliance

Regulatory reliance facilitates regulatory approvals, allows the use of resources more efficiently, and ultimately serves patients by accelerating access to quality-assured, safe, and effective medicines. The World Health Organisation [...]

May 29th, 2024|
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