The CIRS 2025 Annual Report highlights a year of independent research, global stakeholder engagement and evidence-based insights aimed at advancing regulatory and health technology assessment (HTA) policies and processes.

Inside the report, discover key learnings from CIRS research and multi-stakeholder discussions on:

  • Joint Clinical Assessment (JCA) and implementation of the EU HTA Regulation
  • Artificial intelligence (AI) in medicine development, regulation and HTA
  • Patient involvement in regulatory and HTA decision making
  • Global regulatory and HTA benchmarking and performance metrics
  • Regulatory strengthening and capacity building through the OpERA Programme
  • Emerging challenges and opportunities affecting patient access to medicines worldwide.

The report also showcases CIRS’ 2025 outputs, including R&D Briefings, peer-reviewed publications, workshops, forums and international collaborations that brought together regulators, HTA agencies, industry, academia, payers and patient organisations

Download the report to explore the evidence, insights and collaborations shaping the future of regulatory science and HTA.

Our year in numbers

2025 in numbers: 6 R&D Briefings, 12 journal publications, 18 conference presentations, 7 workshops and fora, more than 100,000 website downloads, and engagement with regulators, HTA agencies, industry, academia and patient organisations worldwide.

CIRS Publications

Explore more CIRS Publications

Visit our Publications Library to access the latest R&D Briefings, workshop reports, journal publications and conference posters.
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